Fig. 2 | npj Breast Cancer

Fig. 2

From: Tracking plasma DNA mutation dynamics in estrogen receptor positive metastatic breast cancer with dPCR-SEQ

Fig. 2

ESR1, PIK3CA and TP53 ctDNA mutations in MBC patients. a Progression-free survival of patients with any mutation in ESR1, PIK3CA, or TP53 relative to patients with none of these mutations detected by either dPCR-SEQ or dPCR. Two-tailed P values calculated using the logrank test. b Dynamic changes in MAF for ESR1, PIK3CA, and TP53 in plasma ctDNA. c Stacked histogram plots of cumulative MAF for ESR1, PIK3CA, and TP53 in seven patients demonstrate heterogeneous ctDNA mutation dynamics during systemic therapy

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