Table 1 Clinicopathological and selected genetic features of the 13 breast adenomyoepitheliomas included in this study

From: Assessment of HMGA2 and PLAG1 rearrangements in breast adenomyoepitheliomas

Case ID

ER status

PIK3CA status

AKT1 status

PIK3R1 status

HRAS status

Oncogenic fusion genes by RNA sequencing

PLAG1/ HMGA2 rearrangement by FISH

AM1

Negative

MUT

WT

WT

MUT

NT

Negative

AM4

Negative

MUT

WT

WT

MUT

NT

Negative

AM8

Negative

MUT

WT

WT

MUT

NT

Negative

AM11

Negative

MUT

WT

NT

MUT

NT

Negative

AM5

Negative

WT

WT

MUT

MUT

NT

Negative

AM7

Negative

MUT

WT

WT

WT

None

Negative

AM2

Positive

MUT

WT

WT

WT

None

Negative

AM3

Positive

MUT

WT

WT

WT

None

Negative

AM12

Positive

MUT

WT

NT

WT

NT

Negative

AM13

Positive

MUT

WT

NT

WT

NT

Negative

AM17

Positive

MUT

WT

NT

WT

NT

Negative

AM16

Positive

WT

WT

NT

WT

HMGA2-WIF1

Positive (HMGA2)

AM6

Positive

WT

WT

WT

WT

None

Negative

  1. ER estrogen receptor, MUT mutant, NT not tested, WT wild-type