Fig. 7 | npj Breast Cancer

Fig. 7

From: NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients

Fig. 7

NDRG4 knockdown enhances β1 integrin-mediated cell migration towards vitronectin (VN). Migration to VN (10 μg/ml) is specifically inhibited by the anti-β1 integrin monoclonal antibody (MAB1965) with function-blocking activity. Cells incubated with the anti-αvβ5 integrin monoclonal antibody (clone P1F6) with function-blocking activity and cells incubated with irrelevant IgG were used as controls Error bars represent SEM of biological replicates (n = 3). *p < 0.05, **p < 0.01, ns = not significant by two-tailed t tests

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