Table 1 Descriptive statistics of TDLU involution measures.

From: Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast

Characteristic

Overall (N = 1398)

Komen Tissue Bank (N = 1089)

BREAST Stamp Project (N = 309)

Age (years), n (%)

 <30

318 (22.7)

318 (29.2)

0

 30–39

234 (16.7)

234 (21.5)

0

 40–49

431 (30.8)

274 (25.2)

157 (50.8)

 50–59

301 (21.5)

186 (17.1)

115 (37.2)

 ≥60

114 (8.2)

77 (7.1)

37 (12.0)

Menopausal status, n (%)

 Premenopausal

1,053 (76.4)

847 (79.2)

206 (66.7)

 Postmenopausal

325 (23.6)

222 (20.8)

103 (33.3)

Parity, n (%)

 Nulliparous

581 (41.6)

507 (46.6)

74 (23.9)

 Parous

817 (58.4)

582 (53.4)

235 (76.1)

Family history, n (%)

 No

1,081 (77.6)

853 (78.3)

228 (75.0)

 Yes

312 (22.4)

236 (21.7)

76 (25.0)

Observed TDLUs, n (%)

 No

455 (32.5)

369 (33.9)

86 (27.8)

 Yes

943 (67.5)

720 (66.1)

223 (72.2)

TDLU count, median (IQR)

3 (0–11)

3 (0–11)

4 (0–14)

TDLU/(100 mm2), median (IQR)

8.5 (0.0–31.0)

8.4 (0.0–31.8)

9.7 (0.0–26.7)

Median acini count per TDLU, median (IQR)

12 (7–18.5)

12 (7–19)

11 (7.1–16.5)

Median acini count per TDLU (including women with 0 TDLUs), median (IQR)

7 (0–14.5)

7 (0–15)

8 (0–13.5)

(TDLU counts per unit area) * (acini count/TDLU), median (IQR)

2.4 (0.8–6.4)

2.5 (0.9–7.3)

2.1 (0.6–4.7)

(TDLU count per unit area) * (acini count/TDLU) (including women with 0 TDLUs), median (IQR)

0.8 (0–4.2)

0.8 (0–4.2)

0.9 (0–3.2)