Fig. 1: Somatic mutation spectrum and interaction of top 20 genes. | npj Breast Cancer

Fig. 1: Somatic mutation spectrum and interaction of top 20 genes.

From: Molecular landscape and efficacy of HER2-targeted therapy in patients with HER2-mutated metastatic breast cancer

Fig. 1

a Mutation spectrum of the top 20 genes in 105 patients carrying HER2 mutations. HER2 = 0 defined as HER2 amplification negative and HER2 = 1 defined as HER2 amplification positive. b Somatic interactions of the top 20 genes. Pairwise Fisher’s exact test was used to detect significant gene pairs. HER2, human epidermal growth factor receptor 2.

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