Table 1 Patient characteristics.
Characteristics | No. of patients (%) | P | ||
|---|---|---|---|---|
Total (n = 1184) | HER2 wild-type (n = 1079) | HER2 mutant (n = 105) | ||
Age at initial diagnosis | ||||
≤35 Years | 171 (14.4) | 151 (14.0) | 20 (19.0) | 0.160 |
>35 Years | 1013 (85.6) | 928 (86.0) | 85 (81.0) | |
Histopathological | ||||
Invasive ductal carcinoma | 1049 (88.6) | 962 (89.2) | 87 (82.9) | 0.169 |
Invasive lobular carcinoma | 45 (3.8) | 38 (3.5) | 7 (6.7) | |
Mixed invasive ductal and invasive lobular | 2 (0.2) | 2 (0.2) | 0 (0.0) | |
Other | 88 (7.4) | 77 (7.1) | 11 (10.5) | |
HR status | ||||
Positive | 696 (58.8) | 635 (58.9) | 61 (58.1) | 0.182 |
Negative | 422 (35.6) | 380 (35.2) | 42 (40.0) | |
Unknown | 66 (5.6) | 64 (5.9) | 2 (1.9) | |
HER2 status | ||||
Positive | 329 (27.8) | 265 (24.6) | 64 (61.0) | <0.001 |
Negative | 855 (72.2) | 814 (75.4) | 41 (39.0) | |
Molecular subtype | ||||
HR+/HER2− | 522 (44.1) | 488 (45.2) | 34 (32.4) | <0.001 |
HR+/HER2+ | 174 (14.7) | 147 (13.6) | 27 (25.7) | |
HR−/HER2+ | 155 (13.1) | 118 (10.9) | 37 (35.2) | |
HR−/HER2− | 267 (22.6) | 262 (24.3) | 5 (4.8) | |
Unknown | 66 (5.6) | 64 (5.9) | 2 (1.9) | |
