Table 1 Features of CBCS breast cancer cases and controlsa.
From: Inherited predisposition to breast cancer in the Carolina Breast Cancer Study
Cases | Controls | |
|---|---|---|
Total | 1370 (1.000) | 1635 (1.000) |
Age at dx or enrollment | ||
20–29 | 23 (0.017) | 10 (0.006) |
30–39 | 212 (0.155) | 190 (0.116) |
40–49 | 500 (0.365) | 577 (0.353) |
50–59 | 269 (0.196) | 385 (0.235) |
60–69 | 256 (0.187) | 321 (0.196) |
70–74 | 110 (0.080) | 152 (0.093) |
Ancestry by self-report | ||
African-American (AA) | 586 (0.428) | 592 (0.362) |
European-American (EA) | 765 (0.558) | 1016 (0.621) |
Other | 19 (0.014) | 27 (0.017) |
Menopausal status | ||
Pre-menopausal | 606 (0.528) | 624 (0.465) |
Post-menopausal | 542 (0.472) | 719 (0.535) |
Did not specify | 221 (–) | 292 (–) |
1o family history | ||
Breast and ovarian cancer | 8 (0.006) | 4 (0.003) |
Breast cancer only | 213 (0.160) | 194 (0.122) |
Ovarian cancer only | 26 (0.020) | 29 (0.018) |
Neither | 1083 (0.814) | 1365 (0.857) |
Unknown | 38 (–) | 43 (–) |
TNBC | ||
Yes | 307 (0.254) | |
No | 904 (0.746) | |
Unknown | 159 (–) | |
Tumor subtype | ||
Basal-like | 156 (0.179) | |
Luminal A | 475 (0.545) | |
Luminal B | 84 (0.096) | |
HER2 + ER− | 51 (0.059) | |
Negative for all markers | 105 (0.121) | |
Unknown | 499 (–) | |
Grade | ||
Grade 1 | 152 (0.280) | |
Grade 2 | 165 (0.304) | |
Grade 3 | 225 (0.415) | |
Unknown | 809 (–) | |
Nodal involvement | ||
Yes | 466 (0.354) | |
No | 849 (0.646) | |
Unknown | 36 (–) | |
