Fig. 8: Limited stroma within tumors as a cause of variation in sTIL assessment in breast cancer.
From: Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

Difficulties in sTIL assessment related to stroma include a tumor with small volume of intratumoral stroma present for evaluation; b large areas of necrosis which decrease scorable stromal component; and c mucinous tumors.