Fig. 3: Differential gene expression analysis by subtype. | npj Breast Cancer

Fig. 3: Differential gene expression analysis by subtype.

From: Skeletal muscle reprogramming by breast cancer regardless of treatment history or tumor molecular subtype

Fig. 3

Venn diagram representing DEGs in muscle in each molecular subtype (a) and corresponding area-representative Chow–Ruskey diagram (b). Chi-square analysis of the number of DEGs uniquely differentially expressed in each subtype, the number of DEGs involved in two- and three-way overlaps among subtypes, showing the log-fold change between observed and expected numbers in each category. The chi-square critical value of 12.592 (6 degrees of freedom) is denoted on the chi-square y-axis by a gray horizontal line. A chi-square value larger than 12.592 is statistically significant at α = 0.05 (c).

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