Fig. 2: Tumor immune phenotypes and clinical outcome by ancestry. | npj Breast Cancer

Fig. 2: Tumor immune phenotypes and clinical outcome by ancestry.

From: Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry

Fig. 2

a Heatmap of ICR gene expression in TCGA and RA-QA breast cancer cohorts. Classification of samples by ICR consensus clustering segregates TCGA samples in ICR low, ICR medium, and ICR high groups. Samples of RA-QA cohort were classified as ICR low or ICR high. b Kaplan–Meier plots showing overall survival across ICR groups in breast cancer TCGA patients of EA (left), TCGA patients of AA (middle), and RA-QA patients of ArA (right). c ICR enrichment scores across ancestries within TDA signature classes. Box plots indicate medians and interquartile range, and whiskers represent 10th and 90th percentile. All data points are plotted individually. d Overall survival of EA and AA patients in TCGA BasalMyo samples classified as ICR medium + low (left), and ICR high (right). Censor points are indicated by vertical lines.

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