Table 1 Averaged conversion factors for each gene expression level in the Recurrence Score (RS) signature measured by NanoString.

From: Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna®

Gene

β0,ca

βcb

Proliferation

 MKI67

−0.085231

0.911335

 BIRC5

−1.827968

0.936659

 CCNB1

−1.116226

0.881016

 MYBL2

2.025348

0.539252

 AURKA

3.055030

0.586925

Oestrogen

 PGR

0.832910

0.801175

 SCUBE2

−1.293122

0.979588

 BCL2

1.700006

0.824674

 ESR1

0.545113

0.862295

HER2

 GRB7

1.049809

0.775301

 ERBB2

0.207291

0.887745

Invasion

 MMP11

−0.316719

0.961213

 CTSL2

4.093753

0.308125

Other

 BAG1

−0.399193

0.872163

 CD68

1.407529

0.773401

 GSTM1

6.066959

0.149010

  1. aIntercepts.
  2. bSlopes.
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