Fig. 2: Recurrent somatic TERT, TP53, PIK3CA, HRAS, and BRAF genetic alterations in distinct histologic subtypes of 60 metaplastic breast cancers.
From: TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer
Heatmap depicting the proportion of the histologic component, frequency of TERT genetic alterations, TP53 mutations, PIK3CA mutations, HRAS mutations and BRAF genetic alterations in 60 MBCs. Mutation types are color-coded according to the legend. Cases are shown in columns, the percentage of the histological components, matrix producing, ER and HER2 status, and sequencing methods are depicted in phenobars. *Mutual exclusivity analysis, CoMEt, p < 0.001.
