Table 2 Frequency of genetic alterations affecting TERT gene in 60 metaplastic breast cancers according to their predominant histologic component.

From: TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer

  

Predominant histologic component

 

MBCs

SQUAMOUS

SPINDLE

OSSEOUS

CHONDROID

p valuea

(n = 60)

(n = 14)

(n = 16)

(n = 5)

(n = 25)

 

TERT genetic alteration

10 (17%)

3 (21%)

5 (31%)

2 (40%)

0

0.005

TERT wild-type

50 (83%)

11 (79%)

11 (69%)

3 (60%)

25 (50%)

 
  1. aStatistical significance was evaluated by Fisher’s exact test.