Fig. 1: Characteristics of tumours with germline and somatic alterations in PALB2, BRCA1 and BRCA2.
From: Characterisation of PALB2 tumours through whole-exome and whole-transcriptomic analyses
a Phenobar showing the allelic status, pathology and molecular characteristics of tumours. b Comparison of gene expression between tumours with germline and somatic PTV alterations, and tumour with no alterations (non-carriers). c Comparison of gene expression between tumours with biallelic inactivation, monoallelic inactivation and tumour with no alterations (non-carriers). Boxplots represent medians (centre line) and interquartile range, and whiskers represent the maximum and minimum values within 1.5 times the interquartile range from the edge of the box. Each data point represents an individual sample. P values: Comparison of each category vs non-carrier. ***p < 0.001; **p < 0.01; *p < 0.05; Mann–Whitney U test.
