Table 4 Multivariate Cox regression analyses for DFS in Luminal B breast cancer including immune signatures.
From: The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer
DFS | Multivariate | ||
|---|---|---|---|
N | HR [95%CI] | p-value | |
ICR score | 1438 | 0.84 [0.73–0.97] | 1.95E−02 |
CINSARC classes | 1438 | 1.47 [1.22–1.78] | 7.29E−05 |
TIS score | 1438 | 0.89 [0.79–1.01] | 0.074 |
CINSARC classes | 1438 | 1.46 [1.20–1.76] | 1.09E−04 |
TLS score | 1438 | 0.83 [0.72–0.95] | 8.46E−03 |
CINSARC classes | 1438 | 1.47 [1.22–1.78] | 6.79E−05 |
Palmer, B-cells module | 1438 | 0.32 [0.23–0.45] | 4.62E−11 |
CINSARC classes | 1438 | 1.44 [1.19–1.74] | 1.50E−04 |
Palmer, CD8 T-cells module | 1438 | 0.60 [0.53–0.68] | 3.58E−15 |
CINSARC classes | 1438 | 1.43 [1.19–1.73] | 1.90E−04 |
Palmer, T-cells module | 1438 | 0.35 [0.25–0.48] | 2.32E−10 |
CINSARC classes | 1438 | 1.45 [1.20–1.75] | 1.19E−04 |
Rooney, Cytolytic activity | 1438 | 0.86 [0.77–0.95] | 3.09E−03 |
CINSARC classes | 1438 | 1.45 [1.20–1.75] | 1.37E−04 |
