Table 6 List of 16 proteins/phosphoproteins differentially expressed between the two CINSARC classes in Luminal B TCGA breast cancers.
From: The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer
Gene#Protein | CINSARC, high- vs. low-risk | Expression status | |||
|---|---|---|---|---|---|
N | Odds ratio [95%CI] | p-value | q-value | ||
CCNB1#Cyclin_B1 | 240 | 1.66 [1.41–1.96] | 6.53E−07 | 1.46E−04 | up CINSARC high-risk |
MSH6#MSH6 | 240 | 1.32 [1.19–1.47] | 1.38E−05 | 1.03E−03 | up CINSARC high-risk |
FOXM1#FoxM1 | 240 | 1.31 [1.20–1.44] | 2.31E−06 | 2.58E−04 | up CINSARC high-risk |
RPS6KB1#p70S6K | 240 | 1.28 [1.11–1.47] | 3.86E−03 | 0.086 | up CINSARC high-risk |
SYK#Syk | 240 | 1.26 [1.10–1.44] | 4.65E−03 | 0.093 | up CINSARC high-risk |
ENY2#ENY2 | 218 | 1.23 [1.10–1.37] | 2.46E−03 | 0.063 | up CINSARC high-risk |
YWHAZ#14-3-3_zeta | 240 | 1.20 [1.09–1.33] | 2.21E−03 | 0.063 | up CINSARC high-risk |
ASNS#ASNS | 240 | 1.20 [1.08–1.33] | 5.48E−03 | 0.093 | up CINSARC high-risk |
KAT2A#GCN5L2 | 218 | 1.19 [1.07–1.32] | 6.22E−03 | 0.093 | up CINSARC high-risk |
XRCC5#Ku80 | 240 | 1.15 [1.06–1.25] | 6.65E−03 | 0.093 | up CINSARC high-risk |
CCNE2#Cyclin_E2 | 240 | 1.13 [1.06–1.20] | 1.10E−03 | 0.061 | up CINSARC high-risk |
EIF4EBP1#4E-BP1_pT70 | 240 | 1.12 [1.05–1.20] | 6.61E−03 | 0.093 | up CINSARC high-risk |
CDKN1B#p27_pT198 | 240 | 1.09 [1.03–1.14] | 6.07E−03 | 0.093 | up CINSARC high-risk |
RAD50#Rad50 | 240 | 0.88 [0.83–0.94] | 1.71E−03 | 0.063 | down CINSARC high-risk |
ERCC5#ERCC5 | 240 | 0.87 [0.81–0.94] | 2.17E−03 | 0.063 | down CINSARC high-risk |
MAPK8#JNK_pT183_pY185 | 240 | 0.86 [0.79–0.93] | 2.56E−03 | 0.063 | down CINSARC high-risk |
