Table 1 Characteristics of breast cancer cases and matched controls at blood collection in the Nurses’ Health Study II, mean (SD) or %.

From: Circulating amino acids and amino acid-related metabolites and risk of breast cancer among predominantly premenopausal women

 

Cases (n = 1057)

Controls (n = 1057)

Age at blood collectiona (y)

44.7 (4.5)

44.8 (4.4)

Age at menarche (y)

12.4 (1.3)

12.8 (1.4)

Time between sample collection and diagnosis (y)

8.0 (4.4)

 

Parity and age at first birth (%):

Nulliparous

21.1

15.9

1–2 children, ≥25 y

39.2

34.9

1–2 children, <25 y

14.7

15.9

3+ children, <25 y

11.3

16.6

3+ children, ≥25 y

13.8

14.2

Ever breastfed (%)

63.1

65.0

Family history of breast cancer (%)

17.4

10.8

Personal history of benign breast disease (%)

22.1

15.6

BMI at age 18 (kg/m2)

20.8 (2.9)

21.1 (3.1)

Weight change between age 18 and blood collection (kg)

11.6 (12.0)

12.6 (13.2)

Physical activity, MET-h/wk

18.0 (15.3)

18.1 (15.5)

Alcohol consumption (g/day)

3.8 (6.9)

3.3 (5.6)

Past/current exogenous hormone useb (%)

86.3

86.7

Menopausal status at blood collectiona (%)

Premenopausal

80.2

79.7

Postmenopausal

12.7

13.1

Unknown

7.1

7.3

Menopausal status at diagnosisa (%)

Premenopausal

42.0

42.2

Postmenopausal

46.4

47.1

Unknown

11.6

10.7

Caucasiana (%)

97.2

98.4

Fasting (>8 h) at blood collectiona (%)

68.7

74.7

  1. aMatching factor
  2. bOral contraceptive or menopausal hormone therapy