Fig. 1: Workflow for intraoperative MS of surgical breast tissue.
From: Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery
a Lumpectomy, (b) tissue allocation, (c) tissue smear using squash prep, (d) surface extraction using liquid microjunction surface sample probe (LMJ-SSP), and (e) metabolite profiles generated using electrospray ionization-ion-trap mass spectrometry. *Tumor and normal samples allocated in the frozen section room when adequate tissue is available for diagnosis.
