Fig. 2: Individual levels of Ki67 at baseline, week 2 and surgery.

In cohort B, in 1 of 26 cases at week 2 the tumor block failed to reveal the presence of invasive cells and a pCR was reached at surgery. At surgery, residual invasive disease was present in 22 patients while 5 patients achieved a pathological complete remission with no invasive cells in the breast and axilla. In cohort C, all the 23 cases presented invasive cells at week 2 and at surgery.