Fig. 3: Somatic mutation profiles of breast cancers from MMR variant carriers. | npj Breast Cancer

Fig. 3: Somatic mutation profiles of breast cancers from MMR variant carriers.

From: Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients

Fig. 3

a Landscape of frequently mutated genes in breast cancers from MMR variant carriers. b Comparison of the somatic mutation rates of PIK3CA, TP53, PTEN, and ARID1A between breast cancers carrying MMR germline variants and general breast cancers. Data are analyzed for statistical significance using Fisher’s exact test. Two-sided P values < 0.05 were considered to be statistically significant.

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