Fig. 2: Forest plot of RFS with immune-subset signatures in the NCCTG N9831 with chemotherapy-only arm (AC–T) in blue and sequential (AC–T–H) or concurrent trastuzumab arm (AC–TH) in red.

The HR on the forest plots was from multivariate models adjusting for age, nodal status, ER/PR status, tumor size, and tumor grade. The size of the box in the forest plots represents the precision (standard error) of the estimates.