Table 3 Multivariable logistic regression model of predictors of achieving pCRa.
OR | (95% CI) | p-value | |
|---|---|---|---|
cT2 stage (ref = cT1) | 1.07 | (0.95, 1.20) | 0.268 |
Multi-agent NAC (ref = single agent) | 1.34 | (1.10, 1.62) | 0.003 |
Hormone receptor+ (ref = HR−) | 0.38 | (0.34, 0.43) | <0.001 |
Histology (ref = ductal) | |||
Lobular | 0.83 | (0.67, 1.02) | 0.072 |
Other | 0.87 | (0.60, 1.27) | 0.467 |
Grade (ref = well-differentiated) | |||
2 | 1.59 | (1.20, 2.11) | 0.001 |
3–4 | 2.17 | (1.64, 2.88) | <0.001 |
Age category (ref = 18–39) | |||
40–69 | 0.97 | (0.83, 1.14) | 0.717 |
70+ | 0.73 | (0.58, 0.93) | 0.011 |
Race (ref = White) | |||
Black | 0.97 | (0.81, 1.15) | 0.724 |
Other | 1.37 | (1.10, 1.71) | 0.005 |
Year of diagnosis (ref = 2013) | |||
2014 | 1.19 | (1.02, 1.40) | 0.032 |
2015 | 1.25 | (1.07, 1.45) | 0.005 |
Charlson Comorbidity Index (ref = 0) | |||
1 | 0.82 | (0.68, 0.99) | 0.036 |
2 | 0.77 | (0.50, 1.17) | 0.222 |
≥3 | 0.80 | (0.42, 1.55) | 0.515 |
