Table 1 Characteristics of included studies.

From: The accuracy of magnetic resonance imaging in predicting the size of pure ductal carcinoma in situ: a systematic review and meta-analysis

Study

Menell

Esserman

Kumar

Ornesti

Marcotte-Bloch

Leung

Allen

Vander- walde

Shin

Baur

Mun

Gruber

Pickles

Rahbara

Rominger

Baek

Daniel

Brennan

Preibsch

Song

Sanderink

Shiraishi

Total/ Mean

Study publication year

2005

2006

2006

2008

2009

2010

2010

2010

2012

2013

2013

2013

2015

2015

2015

2017

2017

2017

2019

2020

2020

2020

NA

DCIS patients (N)

32

45

45

16

33

9

63

11

88

58

212

15

26

20

10

56

225

17

123

50

46

164

1364

DCIS measured in MRI (N)

34

45

45

16

32

9

64

9

88

58

78

15

26

19

10

55

244

17

123

50

46

164

1247

DCIS patients mean age [years (SD)]

53.0

50.0

–

–

59.7 (10.3)

47.5 (8.4)

61.9

–

–

52.0

50.0

–

–

54.9

–

51.0

52.4 (10.3)

–

55.5

–

–

54.0

53.2b (3.2)

Biopsy proven DCIS

Yes

Yes

Yes

Yes

Yes

No

Yes

Yes

No

Some

Yes

No

Yes

Yes

Yes

Some

Yes

Yes

Some

Yes

Yes

NA

NA

MRI field [N (%)]

1.5 T

✓

✓

 

✓

✓

✓

✓

 

✓

✓

✓

✓

  

✓

✓

 

✓

✓

  

✓

15 (68)

3 T

            

✓

✓

  

✓

  

✓

  

4 (18)

NA

  

✓

    

✓

            

✓

 

3 (14)

Contrast type [N (%)]

Gadolinium-based

✓

✓

  

✓

✓

✓

 

✓

✓

✓

✓

✓

✓

✓

✓

✓

✓

✓

✓

 

✓

18 (82)

Gadopentetatec

✓

     

✓

  

✓

✓

   

✓

✓

     

✓

7 (32)

NA

  

✓

✓

   

✓

            

✓

 

4 (18)

Contrast dose (mmol/kg)

0.10

0.10

–

–

0.10

0.20

0.10

–

0.10

0.16

0.20

0.16

0.05

0.10

0.20

0.10

0.10

0.10

0.10

–

–

0.10

0.17d (0.05)

Contrast flow rate (ml/s)

–

1.0

–

–

–

–

3.0

 

–

–

1.0

–

–

2.0

2.0

1.0

2.0

2.5

–

2.0

–

1.0

1.75d (0.23)

MRI captures after contrast (N)

–

2

–

–

3

–

–

–

4

7

5

7

7

3

9

5

6

4

7

5

–

3

5d(2)

DCE-MRI scan timee (s)

–

300

–

–

420

–

480

–

–

525

305

–

420

480

550

300

–

–

525

300

–

240

400d (29)

Temporal resolutione (s)

–

–

–

–

–

90

–

–

–

75

61

–

60

–

55

60

–

90

75

60

–

–

70d (4)

Slice thicknesse (mm)

2.0

2.0

–

–

1.4

1.1

–

–

1.0

1.5

0.9

–

f

1.3

2.0

0.9

3.0

–

1.5

2.0

–

–

1.5d (0.2)

Matrix size (mm)

259 × 192

–

–

–

256 × 256

512 × 512

–

–

224 × 448

512 × 512

–

–

f

440 × 660

512 × 512

384 × 384

280 × 512

–

512 × 512

320 × 320

–

768 × 768

NA

Field of view (cm)g

18 × 18

–

–

–

–

36×36

–

–

17 × 17

40 × 40

34 × 34

 

f

22 × 32

38 × 38

34 × 34

32 × 32

–

40 × 40

32 × 32

–

34 × 34

NA

Patient position

Prone

–

–

Prone

Prone

Prone

Prone

–

–

–

–

–

–

–

Prone

Prone

Prone

–

Prone

Prone

Prone

Prone

NA

Breast coils

Yes

–

–

Yes

Yes

Yes

Yes

–

Yes

Yes

Yes

–

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

NA

Channels/breast coil (N)

–

–

–

–

–

–

8

–

–

–

4

–

8

16

–

–

8

8

7

–

–

–

8d (3)

DCIS Enhancement

mass (%)

34

–

–

–

22

–

–

–

–

46

65

–

–

30

30

60

–

–

–

50

–

20

40b (18)

Non-mass (%)

66

–

–

–

78

–

–

–

–

54

35

–

–

70

70

40

–

–

–

50

–

80

61b (18)

  1. NA non-applicable and “–” non-available.
  2. aIn Rahbar 2015 two different sets of measurements were made using 1.5 and 3 T MRI. Only results for 3 T MRI are presented.
  3. bWeighted mean and SD in brackets.
  4. cGadopentetate dimeglumine is a type of Gadolinium-based contrast. It was the only specified contrast that appeared in the included studies.
  5. dSimple mean and SD in brackets.
  6. eThese parameters refer to the DCE-MRI protocol.
  7. fThis study applies multiple DCE-MRI settings in one protocol, presenting different slice thickness and matrix sizes.
  8. gFor Menell et al. and Leung et al. only the largest fields of view are presented in the table. The abtracted range is 16 × 16 to 18 × 18 for Menell et al. and 20 × 20 to 36 × 36 for Leung et al.
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