Fig. 3: ERα-LBD localizes in the cytoplasm and mitochondria of breast cancer cells. | npj Breast Cancer

Fig. 3: ERα-LBD localizes in the cytoplasm and mitochondria of breast cancer cells.

From: ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance

Fig. 3

a Representative images of ERα staining by immunohistochemistry (IHC) in six different BC cell lines. All histological sections were counterstained with hematoxylin. Scale bar representing 50 μm is shown. Magnification: ×40. b Representative confocal images of BC cells stained for ERα (green), mitochondria/OXPHOS (red) and nuclei/DAPI (blue). For each cell line, merged images and colocalization images are also shown. Color code for colocalization: cyan (ERα-Nuclei, N); yellow (ERα-Mitochondria, M). A scale bar for each image representing 40 μm is shown. Magnification: ×63.

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