Table 2 Most Common Adverse Events (CTCAE G ≥ 2).

From: Ruxolitinib and exemestane for estrogen receptor positive, aromatase inhibitor resistant advanced breast cancer

Toxicity

Grade 2, n (%)

Grade 3, n (%)

Grade 4, n (%)

Total (%)

Anemia

5 (20%)

4 (16%)

0

36%

Hypertension

4 (16%)

4 (16%)

0

32%

Fatigue

4 (16%)

4 (16%)

0

32%

Leukopenia

4 (16%)

3 (12%)

0

28%

Depression

2 (8%)

3 (12%)

0

20%

Anxiety

5 (20%)

0

0

20%

ANC, decreased

2 (8%)

3 (12%)

0

20%

Insomnia

3 (12%)

0

0

12%

Hypothyroidism

3 (12%)

0

0

12%

Nausea

1 (4%)

1 (4%)

0

8%

Anorexia

2 (8%)

0

0

8%

Dizziness

2 (8%)

0

0

8%

Dyspnea

2 (8%)

0

0

8%

Cough

2 (8%)

0

0

8%

Urinary Tract Infection

2 (8%)

0

0

8%

Thrombocytopenia

2 (8%)

0

0

8%