Table 1 Characteristics of breast cancer cases in this study.
From: Predicting breast cancer types on and beyond molecular level in a multi-modal fashion
All | Training cohort | Test cohort | p value | Observer study cohort | |
|---|---|---|---|---|---|
Number | 3360 | 2688 (80.0%) | 672 (20.0%) | – | 168 (5.0%) |
Age | 54 ± 9 | 54 ± 8 | 54 ± 10 | 0.312 | 54 ± 12 |
Tumor size (mm) | 19.9 ± 10.4 | 20.0 ± 10.5 | 19.5 ± 9.9 | 0.285 | 19.2 ± 9.4 |
Grade | 0.057 | ||||
1 | 466 | 370 (13.8%) | 96 (14.3%) | – | 30 (17.9%) |
2 | 1762 | 1386 (51.6%) | 376 (56.0%) | – | 82 (48.8%) |
3 | 1132 | 932 (34.7%) | 200 (29.8%) | – | 56 (33.3%) |
Density category in MG | 0.739 | ||||
A | 411 | 336 (12.5%) | 75 (11.2%) | – | 24 (14.3%) |
B | 1434 | 1132 (42.1%) | 302 (44.9%) | – | 83 (49.4%) |
C | 1314 | 1054 (39.2%) | 260 (38.7%) | – | 55 (32.7%) |
D | 201 | 166 (6.2%) | 35 (5.2%) | – | 6 (3.6%) |
BI-RADS category | 0.313 | ||||
4 (4a, 4b, 4c) | 2052 | 1653 (61.5%) | 399 (59.4%) | – | 89 (53.0%) |
5 | 1308 | 1035 (38.5%) | 273 (40.6%) | – | 79 (47.0%) |
Histologic type | 0.345 | ||||
Invasive ductal carcinoma | 2512 | 2019 (75.1%) | 493 (73.4%) | – | 118 (70.2%) |
Invasive lobular carcinoma | 394 | 312 (11.6%) | 82 (12.2%) | – | 26 (15.5%) |
Others | 454 | 357 (13.3%) | 97 (14.4%) | – | 24 (14.3%) |
Molecular subtypes | 0.126 | ||||
Luminal A | 1494 | 1214 (45.2%) | 280 (41.7%) | – | 67 (39.9%) |
Luminal B | 905 | 721 (26.8%) | 184 (27.4%) | – | 49 (29.2%) |
HER2-enriched | 386 | 298 (11.1%) | 88 (13.1%) | – | 23 (13.7%) |
Triple-negative | 575 | 455 (16.9%) | 120 (17.9%) | – | 29 (17.3%) |
