Table 1 Patient characteristics, entire cohort.

From: Racial disparity in tumor microenvironment and distant recurrence in residual breast cancer after neoadjuvant chemotherapy

 

Number of Patients (%)

 
 

All Patients

N = 183 (100)

Black Patients

N = 96 (52.5)

White Patients

N = 87 (47.5)

P-Value

Distant Recurrence

   

0.07

 Yes

77 (42.1)

47 (49)

30 (34.5)

 

 No

106 (57.9)

49 (51)

57 (65.5)

 

Age

   

0.69

 Mean [SD]

51.9 [11.5]

51.6 [10.3]

52.3 [12.7]

 

 Median [IQR]

52 [44, 60]

51 [45.8, 58.2]

52 [43.5, 61]

 

 Range

28–95

29–78

28–95

 

Time to Distant Recurrence, Months

   

0.62

Mean [SD]

61.9 [40.4]

63.9 [42.9]

59.8 [37.7]

 

 Median [IQR]

62.5 [26.1, 92.9]

60.7 [26.6, 94.3]

64 [25.8, 89.5]

 

 Range

1–160.7

9.4–159.8

1–160.7

 

Surgery

   

0.04

 Mastectomy

114 (62.3)

67 (69.8)

47 (54)

 

 Breast-Conserving Therapy

69 (37.7)

29 (30.2)

40 (46)

 

Tumor Stage (ypT)

   

0.84

 T1 ( < 2 cm)

82 (44.8)

45 (46.9)

37 (42.5)

 

 T2 (2–5 cm)

71 (38.8)

36 (37.5)

35 (40.2)

 

 T3 ( > 5 cm)

30 (16.4)

15 (15.6)

15 (17.2)

 

Lymph Node Status (ypN)

   

0.67

 Positive

130 (71)

70 (72.9)

60 (69)

 

 Negative

53 (29)

26 (27.1)

27 (31)

 

Grade

   

0.002

 1

6 (3.3)

0 (0)

6 (6.9)

 

 2

50 (27.3)

22 (22.9)

28 (32.2)

 

 3

119 (65)

73 (76)

46 (52.9)

 

 Unknown

8 (4.4)

1 (1)

7 (8)

 

Subtype

   

0.1

 ER+/HER2-

91 (49.7)

41 (42.7)

50 (57.5)

 

 TNBC

59 (32.2)

37 (38.5)

22 (25.3)

 

 Other

33 (18)

18 (18.8)

15 (17.2)

 
  1. Wilcoxon rank sum test is used for continuous variables. Chi-squared tests or Fisher’s exact tests are used for categorical variables.
  2. SD Standard deviation, IQR Interquartile range, yPT Tumor stage after neoadjuvant chemotherapy, yPN Lymph node status after neoadjuvant chemotherapy, ER+ Estrogen receptor positive, TNBC Triple negative breast cancer.