Fig. 4: Forest plot from logistic regression model of pathological complete response according to IHC profile and CIT256 profile combined.

A supplementary analysis excluding ER 1ā9% from ER+ resulted in a point estimate of 9.33 for ERā+āHER2- Non-luminal. The boxes represent the weight of data in terms of sample size for each subgroup and the lines represent the 95% confidence interval of the estimated odds ratio. ER Estrogen receptor, HER2 Human epidermal growth factor receptor-2, ER+ ER-positive, ERā ER-negative, HER2+ Her2-positive, HER2ā HER2-negative, Luminal Luminal A, Luminal B Normal-like, Non-luminal Basal-like, HER2-enriched, pCR Pathological complete response (Residual Cancer Burden 0), OR odds ratio, IHC Immunohistochemistry.