Table 4 Characteristics of distant recurrence cases in the study cohort.

From: Second breast cancer: recurrence score results, clinicopathologic characteristics, adjuvant treatments, and outcomes—exploratory analysis of the Clalit registry

#

Age at 1st testing, years

Nodal status at 1st testing

RS, 1st testing

Surgery

Treatment received after first testing

Duration between ET discontinuation and 2nd testing

Duration between 1st and 2nd testing, years

RS, 2nd testing

Ipsilateral/ contralateral BC

Treatment received after 2nd testing

Duration between 2nd testing and metastatic disease, years

1

36

N1

10

Lumpectomy

RT + CT

NA

3.5

13

Ipsilateral

ET

2.3

2

56

N0

19

Lumpectomy

RT + ET

Progressed on ET

1.03

22

Ipsilateral

ET

5.0

3

55

N0

21

NA

RT + ET

Progressed on ET

3.9

62

Ipsilateral

CT

0.7

4

47

N1mi

24

Lumpectomy

RT + ET

Progressed on ET

3.2

33

Ipsilateral

ET + CT

1.8

5

59

N0

26

Lumpectomy

RT + ET

NA

5.5

38

Ipsilateral

ET + CT

3.9

  1. BC breast cancer, CT chemotherapy, ET endocrine therapy, NA not available, RS Recurrence Score, RT radiation therapy.