Table 2 Factors associated with cancer recurrence or death by multivariable Cox proportional hazards model.

From: Tamoxifen or aromatase inhibitors with ovarian function suppression in pre-menopausal stage I-III lobular breast cancer

Variable

Hazard Ratio

95% CI

p-value

Adjuvant endocrine therapy (longest received)

SERM

AI

0.31

0.11–0.86

0.025

Age at diagnosis (above & below median)

30–46 years old

47–56 years old

0.61

0.24–1.56

0.304

Histologic grade

Grade 1 or 2

Grade 3

6.63

1.4–31.3

0.02

Tumor size

Tumor size, cm

1.02

0.88–1.19

0.773

Lymph node positivity

Number of positive nodes

1.10

1.03–1.18

0.003

Receipt of ovarian suppression

No OFS

Received OFS

3.77

1.33–10.7

0.013

  1. AI aromatase inhibitor, SERM selective estrogen receptor modulator, OFS ovarian function suppression.
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