Table 1 Overview of sociodemographic and clinical characteristics by postoperative surgical complications statusa

From: Allostatic load as a predictor of postoperative complications in patients with breast cancer

Patient characteristic

All

Postoperative Surgical Complications

P-Valueb

Yes

No

n = (4459)

n = (365)

n = (4094)

Age group, n (%)

   

0.103

≤39

313 (7)

17 (4.7)

296 (7.2)

 

40–49

838 (18.8)

70 (19.2)

768 (18.8)

 

50–59

1184 (26.6)

85 (23.3)

1099 (26.8)

 

60–59

1286 (28.8)

112 (30.7)

1174 (28.7)

 

70+

838 (18.8)

81 (22.2)

757 (18.5)

 

Race-ethnicity, n (%)

   

0.095

Hispanic-Black

3 (0.1)

0 (0)

3 (0.1)

 

Non-hispanic-Black

381 (8.5)

46 (12.6)

335 (8.2)

 

Hispanic-White

23 (0.5)

1 (0.3)

22 (0.5)

 

Non-hispanic-White

3861 (86.6)

302 (82.7)

3559 (86.9)

 

Hispanic-other

27 (0.6)

3 (0.8)

24 (0.6)

 

Non-hispanic-other

164 (3.7)

13 (3.6)

151 (3.7)

 

Marital status, n (%)

   

0.002

Single

639 (14.3)

63 (17.3)

576 (14.1)

 

Married/living as married

2843 (63.8)

202 (55.3)

2641 (64.5)

 

Widowed, separated or divorced

977 (21.9)

100 (27.4)

877 (21.4)

 

Health insurance, n (%)

   

<0.001

Managed care

2650 (59.4)

184 (50.4)

2466 (60.2)

 

Medicaid

1365 (30.6)

130 (35.6)

1235 (30.2)

 

Medicare

376 (8.4)

46 (12.6)

330 (8.1)

 

Other

68 (1.5)

5 (1.4)

63 (1.5)

 

Smoking history, n (%)

   

0.082

Never

2787 (62.5)

211 (57.8)

2576 (62.9)

 

Current or former

1672 (37.5)

154 (42.2)

1518 (37.1)

 

Alcohol use, n (%)

   

0.029

Never

2103 (47.2)

192 (52.6)

1911 (46.7)

 

Current or former

2356 (52.8)

173 (47.4)

2183 (53.3)

 

Charlson comorbidity indexc, n (%)

   

<0.001

0

3520 (78.9)

248 (67.9)

3272 (79.9)

 

1–3

826 (18.5)

92 (25.2)

734 (17.9)

 

4+

113 (2.5)

25 (6.8)

88 (2.1)

 

HER-2+ summary, n (%)

692 (15.5)

59 (16.2)

633 (15.5)

0.703

Progesterone+ summary, n (%)

3111 (69.8)

255 (69.9)

2856 (69.8)

0.967

Estrogen+ summary, n (%)

3569 (80.0)

288 (78.9)

3281 (80.1)

0.571

Molecular subtype, n (%)

   

0.796

Hormone receptor negative/HER 2 positive

242 (5.4)

24 (6.6)

218 (5.3)

 

Hormone receptor positive/HER 2 negative

2753 (61.7)

223 (61.1)

2530 (61.8)

 

Hormone receptor positive/HER2 positive

818 (18.3)

66 (18.1)

752 (18.4)

 

Hormone receptor negative/HER negative

646 (14.5)

52 (14.2)

594 (14.5)

 

Cancer stage, n (%)

   

0.206

1

2814 (63.1)

211 (57.8)

2603 (63.6)

 

2

1369 (30.7)

121 (33.2)

1248 (30.5)

 

3

276 (6.2)

33 (9.0)

243 (5.9)

 

Mastectomy, n (%)

2124 (47.6)

187 (51.2)

1937 (47.3)

0.151

Lumpectomy, n (%)

2306 (51.7)

201 (55.1)

2105 (51.4)

0.180

Sentinel lymph node biopsy only, n (%)

1444 (32.4)

94 (25.8)

1350 (33.0)

0.005

Axillary lymph node biopsy only, n (%)

237 (5.3)

20 (5.5)

217 (5.3)

0.884

Both sentinel and axillary lymph node biopsies, n (%)

2013 (45.1)

187 (51.2)

1826 (44.6)

0.015

Reconstructive surgery

1156 (25.9)

78 (21.4)

1078 (26.3)

0.038

Hormone therapy, n (%)

3355 (75.2)

272 (74.5)

3083 (75.3)

0.739

Radiation therapy, n (%)

2679 (60.1)

216 (59.2)

2463 (60.2)

0.713

Chemotherapy, n (%)

2112 (47.4)

184 (50.4)

1928 (47.1)

0.224

High allostatic load, n (%)

2202 (49.4)

213 (58.4)

1989 (48.6)

<0.001

  1. aEither technical, cardiovascular, respiratory, urinary, or infectious postoperative complications
  2. bP-value from Wilcoxon rank sum test for age but p-values from Chi-Square tests to test the association between postoperative complications and other patient characteristics
  3. cUsing Charlson Comorbidity Index weights (excluding cancer)