Fig. 4: Effect of chemotherapy on CD4+ and CD8+ T cell subsets.
From: Sustained lymphocyte decreases after treatment for early breast cancer
Paired t-test show differences in between post- and pre-chemotherapy T cell subsets in matched pairs from pre-menopausal (a) and all patients (b). Post-chemotherapy change in recent thymic emigrant (CD31+CCR7+CD45RA+) CD4+ T cells for pre- and post-menopausal patients is shown in (c), and post-chemotherapy change in CD8+/CD25+ FOXP3+ T regulatory ratio in pre- and post-menopausal patients is shown in (d). Individual dots represent values for individual patient values. P-value shown for paired t-tests. TEMRA terminally differentiated memory cells.
