Fig. 4: Comutation plot depicting commonly altered genes in 40/42 (95%) samples that underwent initial next generation sequencing.

Notably, one patient with MRD did not have significantly overlapping genomic variants and thus is not listed in the above plot. Additional clinical data includes minimal residual disease status, stage, hormone receptor status, prior endocrine therapy duration, and identity of prior endocrine therapy. MRD minimal residual disease, ER estrogen receptor; PR progesterone receptor; ET endocrine therapy.