Fig. 4: DEGs for the most relevant signatures in PABC.

a Volcano plot of DE in PABC vs non-PABC with the DNA damage repair genes highlighted in orange. b Heat map for the most DEGs of the DNA damage repair signature (|FC| ≥ 1.5 and FDR < 0.05) in PABC (red) and non-PABC (green). c Volcano plot of DE in PABC vs non-PABC with the proliferation genes highlighted in orange. d Heat map for the most DEGs of the proliferation signature (|FC| ≥ 1.5 and FDR < 0.05) in PABC (red) and non-PABC (green). e Volcano plot of the DE in PABC vs non-PABC with the subtypes-related genes highlighted in orange. f Heat map for the most DEGs of the subtypes signature (|FC| ≥ 1.5 and FDR < 0.05) in PABC (red) and non-PABC (green).