Fig. 7: Pathway and cell-type profiling analysis between subgroups. | npj Breast Cancer

Fig. 7: Pathway and cell-type profiling analysis between subgroups.

From: Molecular characterization of pregnancy-associated breast cancer and insights on timing from GEICAM-EMBARCAM study

Fig. 7

a Graph showing the average scores of the 23 biological pathways/processes from the nCounter BC360 panel according to the gene expression profile between PABC-GS and PABC-PP. b Volcano plot of the DE in PABC-PP vs PABC-GS with the immune infiltration genes highlighted in orange, and on the right a heat map for the 33 genes from the immune infiltration signature in PABC-PP (blue) and PABC-GS (brown), marking with an *those genes with a |FC| ≥ 1.5 and p-value < 0.05. c The graph shows immune cell-type abundance measurements across subgroups of patients (PABC-GS and PABC-PP), according to their gene expression profiles. Each cell type score was centered to zero value; on the right comparative box plot displayed the cell abundance score for the most enrichment cell types in PABC-PP compared to PABC-GS.

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