Table 2 Logistic regression analysis of immune cell proximity and clinical factors in predicting pathologic complete response (pCR)
Variable | Categories | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | ||
CD8+_N20 | Continuous | 9.555 | 1.716–53.196 | 0.011 | 9.509 | 1.331–67.915 | 0.025 |
CD4+_N20 | Continuous | 2.364 | 0.871–6.414 | 0.091 | 6.981 | 1.507–32.342 | 0.013 |
Her-2 | Categorical | 6.848 | 2.047–22.909 | 0.002 | / | / | / |
LN metastases | Categorical | 0.357 | 0.162–0.784 | 0.010 | 0.394 | 0.162–0.957 | 0.040 |
Grade | Categorical | 0.226 | 0.071–0.716 | 0.011 | / | / | / |
TILs_Tumor | Continuous | 1.394 | 0.962–2.019 | 0.079 | / | / | / |