Fig. 2: Estimated genetic ancestry distribution in BEST TNBC RNA-seq cohort. | npj Breast Cancer

Fig. 2: Estimated genetic ancestry distribution in BEST TNBC RNA-seq cohort.

From: Population-specific patterns in assessing molecular subtypes of young black females with triple-negative breast cancer

Fig. 2

Genetic ancestry was estimated from genotypes from multi-locus SNP genotype data with 1000Genomes as the reference. A Relative proportion of ancestry estimation per participant with TNBC from the BEST cohort. B Distribution of participants with “High” proportional West African ancestry (Red) vs. “Low” relative to European ancestry (Blue). C TNBC subtype distribution based on “High” and “low” proportional West African ancestry. D Heatmap of unsupervised hierarchical clustering of ancestry proportion in the BEST cohort (“High” proportional West African ancestry in red vs. “Low” in blue), shown with associated TNBC subtypes.

Back to article page