Fig. 4: Segment-level copy number landscape plots of the combined TNBC samples.

On the x-axis, each of the 534 copy number segments is plotted in relative order, with height above the x-axis corresponding to the gain frequency of the segment within the sample set and height below the x-axis corresponding to the loss frequency of the segment within the sample set. a segment gain/loss frequencies are colored by statistical significance and direction of association of binomial generalized linear models using segment gain/loss status to predict basal-like subtype. Orange-colored segment gains/losses are statistically more significant in basal-like samples vs. non-basal-like samples with (dark orange) and without (light orange) multiple test corrections. Blue-colored segment gains/losses are statistically more significant in non-basal-like samples vs. basal-like samples with (dark blue) and without (light blue) multiple test corrections. b segment gain/loss frequencies are colored by statistical significance and direction of association of Cox proportional hazards models using segment gain/loss status to predict overall survival. Orange-colored segment gains/losses are associated with worse survival, with (dark orange) and without (light orange) multiple test corrections. Blue-colored segment gains/losses are associated with better survival, with (dark blue) and without (light blue) multiple test corrections.