Fig. 2: Single-cell transcriptomic profiling reveals distinct cellular landscapes between primary and relapsed PyMT tumors.
From: Modeling tumor relapse using proliferation tracing and ablation transgenic mouse
a UMAP visualization of tumor cellular composition. Immune cell populations are demarcated by black dashed circles. Neutrophils and NK cells are highlighted with green and blue arrows, respectively. b Dot plot analysis of cell type-specific marker genes. Dot size represents the percentage of cells expressing each gene, while color intensity indicates normalized expression levels. Sankey plot comparing the proportions of CD45+ immune cells (c) and CD45− non-immune cells (d) in primary and relapsed tumors.
