Table 1 Description of study cohort
Description | BRCA1 PV carriers | BRCA2 PV carriers | ||||
---|---|---|---|---|---|---|
Total | Aff (%) | Unaff (%) | Total | Aff (%) | Unaff (%) | |
Total, N | 604 | 390 (100.0) | 214 (100.0) | 785 | 552 (100.0) | 233 (100.0) |
Country | ||||||
Malaysia | 255 | 126 (32.3) | 129 (60.3) | 220 | 143 (25.9) | 77 (33.0) |
Korea | 218 | 159 (40.8) | 59 (27.6) | 359 | 229 (41.5) | 130 (55.8) |
Hong Kong | 67 | 52 (13.3) | 15 (7.0) | 93 | 74 (13.4) | 19 (8.2) |
Singapore | 64 | 53 (13.6) | 11 (5.1) | 113 | 106 (19.2) | 7 (3.0) |
Year of Birth | ||||||
≤1940 | 15 | 6 (1.5) | 9 (4.2) | 16 | 15 (2.7) | 1 (0.4) |
1941-1950 | 40 | 22 (5.6) | 18 (8.4) | 71 | 58 (10.5) | 13 (5.6) |
1951-1960 | 127 | 86 (22.1) | 41 (19.2) | 193 | 140 (25.4) | 53 (22.7) |
1961-1970 | 172 | 118 (30.3) | 54 (25.2) | 256 | 189 (34.2) | 67 (28.8) |
>1970 | 250 | 158 (40.5) | 92 (43.0 | 249 | 150 (27.2) | 99 (42.5) |
Censoring age | ||||||
Mean (SD) | 42.9 (12.0) | 40.9 (10.2) | 46.5 (13.9) | 44.1 (11.4) | 44.3 (10.2) | 43.4 (13.8) |
Range | 19.13-80.91 | 19.73–73.63 | 19.13–80.91 | 19.19–80.94 | 22.74–77.77 | 19.19–80.94 |
Censoring age group | ||||||
≤30 | 74 | 45 (11.5) | 29 (13.6) | 71 | 25 (4.5) | 46 (19.7) |
30-40 | 211 | 165 (42.3) | 46 (21.5) | 239 | 191 (34.6) | 48 (20.6) |
40-50 | 163 | 108 (27.7) | 55 (25.7) | 245 | 184 (33.3) | 61 (26.2) |
50-60 | 94 | 51 (13.1) | 43 (20.1) | 159 | 110 (19.9) | 49 (21.0) |
>60 | 62 | 21 (5.4) | 41 (19.2) | 71 | 42 (7.6) | 29 (12.4) |