Fig. 6

DNAm variability for regulatory elements. Distributions of reference intervals in monocytes a–f and CD4+ T cells g–l. Background distributions are based on the ~24 million CpG sites included in our comprehensive DNAm profiles. CGI CpG island, DHS DNase I-hypersensitive site, H3K27ac histone H3 acetyl Lys27, H3K4me1 histone H3 monomethyl Lys4, H3K4me3 histone H3 trimethyl Lys4, TFBS transcription factor binding site