Table 1 Demographics and clinical characteristics by NGS panel choice, n (%)
From: Predictors of next-generation sequencing panel selection using a shared decision-making approach
Variable | Category | Total (N = 265) | BCP (N = 49) | MCP (N = 216) | p valuea |
|---|---|---|---|---|---|
Demographics | |||||
Age | |||||
<50 | 145 (54.7) | 34 (69.4) | 111 (51.4) | 0.0057 | |
≥50 | 120 (45.3) | 15 (30.6) | 105 (48.6) | ||
Ethnicity | |||||
Chinese | 188 (70.9) | 23 (46.9) | 165 (76.4) | 0.0003 | |
Malay | 24 (9.1) | 6 (12.2) | 18 (8.3) | ||
Indian | 13 (4.9) | 3 (6.1) | 10 (4.6) | ||
Others | 40 (15.1) | 17 (34.7) | 23 (10.6) | ||
Parous | |||||
Yes | 189 (71.3) | 37 (75.5) | 152 (70.4) | 0.4726 | |
No | 76 (28.7) | 12 (24.5) | 64 (29.6) | ||
Personal history of cancer | |||||
Breast cancer | |||||
Yes | 193 (72.8) | 47 (95.9) | 146 (67.6) | 0.0009 | |
No | 72 (27.2) | 2 (4.1) | 70 (32.4) | ||
Ovarian cancer | |||||
Yes | 92 (34.7) | 4 (8.2) | 88 (40.7) | 0.0002 | |
No | 173 (65.3) | 45 (91.8) | 128 (59.3) | ||
Family history of cancer in relativesb | |||||
Any cancer type | |||||
Present | 203 (76.6) | 36 (73.5) | 167 (77.3) | 0.8350 | |
Absent | 62 (23.4) | 13 (26.5) | 49 (22.7) | ||
Breast cancer only | |||||
Present | 33 (12.5) | 6 (12.2) | 27 (12.5) | 0.9508 | |
Absent | 232 (87.5) | 43 (87.8) | 189 (87.5) | ||
Ovarian cancer only | |||||
Present | 7 (2.6) | 1 (2.0) | 6 (2.8) | 0.9985 | |
Absent | 258 (97.4) | 48 (98.0) | 210 (97.2) | ||
Breast and/or ovarian cancer only | |||||
Present | 46 (17.4) | 8 (16.3) | 38 (17.6) | 0.9013 | |
Absent | 219 (82.6) | 41 (83.7) | 178 (82.4) | ||
Colorectal and/or endometrial cancer | |||||
Present | 54 (20.4) | 8 (16.3) | 46 (21.3) | 0.8903 | |
Absent | 211 (79.6) | 41 (83.7) | 170 (78.7) | ||
