Fig. 3: TTN mutation frequency and replication time. | npj Genomic Medicine

Fig. 3: TTN mutation frequency and replication time.

From: Spontaneous mutations in the single TTN gene represent high tumor mutation burden

Fig. 3

a Mutation frequency adjusted by coding sequence (CDS) length. b Mutation frequency adjusted by CDS among TTN, other FLAGS, and remaining 18581 genes (p-value by paired Wilcoxon rank-sum test). c Mutation frequency adjusted by CDS length and by both CDS length and GC content, and mRNA expression level of the top 11 FLAGS, including TTN in CDS length in the MSI-H group. d Association between mutation frequency and replication time in FLAGS, including TTN.

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