Fig. 3: MWAS results from MOA and MOMENT show high correlation of effect sizes in the Australian ALS cohort. | npj Genomic Medicine

Fig. 3: MWAS results from MOA and MOMENT show high correlation of effect sizes in the Australian ALS cohort.

From: Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis

Fig. 3

a −log10(p) of all probes in MOA (x-axis) and MOMENT (y-axis), for the AU ALS dataset. Dashed blue lines mark the genome-wide significance threshold (p = 3.1 × 10−7) of MOA and MOMENT. Red dots mark all probes with p < 5 × 10−4 from MOA (m = 241) as in b. Effect sizes of MOA (x-axis) and MOMENT (y-axis), for AU ALS dataset, of probes with p < 5 × 10−4 from MOA. Correlation of effect sizes: \(\hat r_{\mathrm b} = 0.81\) = 0.81, s.e. = 0.03.

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