Fig. 3: Temporal trends in hospital costs around the time of rWGS testing. | npj Genomic Medicine

Fig. 3: Temporal trends in hospital costs around the time of rWGS testing.

From: Rapid whole genome sequencing impacts care and resource utilization in infants with congenital heart disease

Fig. 3

Evaluation of spending trend surrounding the rWGS process showed an overall decreased spending post rWGS results (Supplementary Table 2b). There is a significant association between time period and cost (p = 0.01; repeated measures ANOVA). Specifically, there is a significant difference in cost between periods 1 and 3 (mean difference 2266.4; 95% CI 1035.6–3497.1; *p = 0.001; paired t-test) and periods 2 and 3 (mean difference 1917.1; 95% CI 1077.2–2756.9; **p = 0.0001; paired t-test). There is not a significant difference in cost between the nondiagnostic and diagnostic groups by time period (p = 0.70; repeated measures ANOVA).

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