Table 1 Top genes across all tissues from the ACT TWAS.

From: Transcriptome-wide association study uncovers the role of essential genes in anthracycline-induced cardiotoxicity

Gene

Z-scorea

P value

Tissue

GDF5

−4.30

1.70 × 10−5

Adipose - subcutaneous

FRS2

4.07

4.67 × 10−5

Pancreas

HDDC2

4.01

6.08 × 10−5

Brain - cortex

EEF1B2

−3.97

7.24 × 10−5

Vagina

  1. aRepresents the number of standard deviations the mean expression of the gene in ACT cases is from that of controls, after adjusting for the weight of each eQTL influencing expression of the gene.
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