Table 1 Baseline characteristics of sequenced participants.

From: Genetic variants associated with inherited cardiovascular disorders among 13,131 asymptomatic older adults of European descent

 

ASPREE

Total population size

13,131

Female sex—no. (%)

7056 (54)

Age at enrolment in years (mean)

75

Age after follow-up in years (mean)

79

Age range in years—no. (%)

70–74 years

7894 (60)

75–79 years

3406 (26)

≥80 years

1831 (14)

Race or ethnic groupa—no. (%)

White/Caucasian

12,953 (99)

Other

178 (1)

Obese (BMI ≥ 30 kg/m2)b (%)

28

Current smoking (%)

4

Heart, stroke or vascular diseasec (%)

0

  1. Participants were enrolled in the ASPREE trial, aged 70 years and older, without a prior history or current diagnosis of atherothrombotic cardiovascular disease, dementia diagnosis, physical disability or life-threating cancer diagnoses.
  2. aSelf-report.
  3. bObese was defined as body-mass index (weight in kilograms divided by the square of the height in meters) of ≥30.
  4. cDefined by the ASPREE (ASPirin in Reducing Events in the Elderly) Study Protocol.