Table 1 Clinicopathological characteristics.

From: Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer

 

Primary CRC (n = 315 patientsa)

Metastatic CRC (n = 176 patientsa)

No. of patients

%

No. of patients

%

Age at surgery

 Below 65 years

94

30

81

46

 65–75 years

105

33

76

43

 Above 75 years

116

37

19

11

Gender

 Male

169

54

110

62

 Female

146

46

66

38

Primary tumor location

 Left/rectum

181

57

133

76

 Right

126

40

35

20

 Synchronous

7

2

1

1

 Unknown

1

0.3

7

4

Cancer stage at first diagnosis

 I

65

21

2

1

 II

117

37

15

9

 III

90

29

112

64

 IV

41

13

31

18

 Unknown

2

1

16

9

Diagnosis of liver metastasis

 Synchronous (within 6 months of initial diagnosis)

138

78

 Metachronous

38

22

Systemic oncological treatment prior to sampling of metastases

 Neoadjuvant chemotherapy for this metastatic situation

134

76

 Previous chemotherapy only

27

15

 No previous systemic treatment (naive)

15

9

  1. aFourteen patients with matched primary and metastatic tumor samples.