Fig. 4: Segmental imbalances in cleavage embryos.
a Rate and distribution of various types of segmental imbalances across the genome (n = 162, 91, and 41 for deletions, duplications and complex imbalances, respectively). b Correlation of chromosome-specific rate of segmental imbalances with chromosome length (R2 = 0.69, P < 0.0001). Boxplot comparison of simple segmental imbalances (n = 253) by nature (deletions vs. duplications) (c), location (p-arm vs. q-arm) (d) and parental origin (maternal vs. paternal) (e). Two-tailed t-test, **P = 0.008, *P = 0.02.
