Fig. 4: False positive rate for COSMIC mutations in TP53. | npj Genomic Medicine

Fig. 4: False positive rate for COSMIC mutations in TP53.

From: Accurate detection of circulating tumor DNA using nanopore consensus sequencing

Fig. 4

False positive (FP) rate was obtained for four representative runs: two runs based on a single TP53 exon, one run covering multiple TP53 exons, and one run covering all TP53 exons. For each COSMIC position in the target insert, the FP was calculated. The y-axis represents the percentage of bases having a snFP value lower than the FP indicated at the corresponding X-value. Blue is CY_PJET_12WT_0001_000, yellow is CY_SS_PC_HC_0001_001_000, green is CY_SM_PC_HC_0002_001_000, and red is CY_SM_PC_HC_0004_001_000.

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